Oxidative Stress: A Culprit in the Progression of Diabetic Kidney Disease
Union Hospital · Huazhong University of Science and Technology
Abstract
Diabetic kidney disease (DKD) is the principal culprit behind chronic kidney disease (CKD), ultimately developing end-stage renal disease (ESRD) and necessitating costly dialysis or kidney transplantation. The limited therapeutic efficiency among individuals with DKD is a result of our finite understanding of its pathogenesis. DKD is the result of complex interactions between various factors. Oxidative stress is a fundamental factor that can establish a link between hyperglycemia and the vascular complications frequently encountered in diabetes, particularly DKD. It is crucial to recognize the essential and integral role of oxidative stress in the development of diabetic vascular complications, particularly…
Citation impact
- FWCI
- 52.39
- Percentile
- 100%
- References
- 344
Authors
2Topics & keywords
- Culprit
- Oxidative stress
- Medicine
- Disease
- Diabetes mellitus
- Kidney disease
- Internal medicine
- Bioinformatics
- Good health and well-being
Funding
- NNNational Natural Science Foundation of ChinaAwards: 81974097, 82170773, 82100729, 82200808, 82370728, 2023BCB034, 82200841, 82300843, 82300786, 81974096, 2021YFC2500200
- NKNational Key Research and Development Program of ChinaAwards: 82370728, 82300786, 2021YFC2500200, 2023BCB034, 82300843, 81974097, 81974096, 82170773, 82200808, 82200841, 82100729