Breaking the pH Limitation of Nanozymes: Mechanisms, Methods, and Applications

Feng, Kaizheng; Wang, Guancheng; Wang, Shi; Ma, Jingyuan; Wu, Haoan; Ma, Ming; Zhang, Yu

doi:10.1002/adma.202401619

reviewAdvanced MaterialsApr 14, 2024Closed access

Breaking the pH Limitation of Nanozymes: Mechanisms, Methods, and Applications

KFKaizheng Feng GWGuancheng Wang SWShi Wang JMJingyuan Ma HWHaoan Wu

Ministry of Education and Child Care · State Key Laboratory of Digital Medical Engineering · +1 more institution

PubMed

Indexed incrossrefpubmed

Abstract

Although nanozymes have drawn great attention over the past decade, the activities of peroxidase-like, oxidase-like, and catalase-like nanozymes are often pH dependent with elusive mechanism, which largely restricts their application. Therefore, a systematical discussion on the pH-related catalytic mechanisms of nanozymes together with the methods to overcome this limitation is in need. In this review, various nanozymes exhibiting pH-dependent catalytic activities are collected and the root causes for their pH dependence are comprehensively analyzed. Subsequently, regulatory concepts including catalytic environment reconstruction and direct catalytic activity improvement to break this pH restriction are…

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152

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FWCI: 16.52
Percentile: 100%
References: 286

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Keywords

Materials science
Nanotechnology

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