Immunotherapy and the ovarian cancer microenvironment: Exploring potential strategies for enhanced treatment efficacy
Central South University · BC Platforms (Finland) · +3 more institutions
Abstract
Despite progress in cancer immunotherapy, ovarian cancer (OC) prognosis continues to be disappointing. Recent studies have shed light on how not just tumour cells, but also the complex tumour microenvironment, contribute to this unfavourable outcome of OC immunotherapy. The complexities of the immune microenvironment categorize OC as a 'cold tumour'. Nonetheless, understanding the precise mechanisms through which the microenvironment influences the effectiveness of OC immunotherapy remains an ongoing scientific endeavour. This review primarily aims to dissect the inherent characteristics and behaviours of diverse cells within the immune microenvironment, along with an exploration into its reprogramming and…
Citation impact
- FWCI
- 36.03
- Percentile
- 100%
- References
- 204
Authors
7- ZWZhibin Wang
Central South University, BC Platforms (Finland), Hunan Cancer Hospital
- XZXiu Zhang
Central South University, BC Platforms (Finland), Hunan Cancer Hospital
- CFChao Fang
Central South University, Changsha Medical University, Hunan Cancer Hospital
- XLXiaoting Liu
Second People Hospital of Hunan
- QLQianjin Liao
Central South University, BC Platforms (Finland), Hunan Cancer Hospital
Topics & keywords
- Tumor microenvironment
- Immunotherapy
- Immune system
- Cancer immunotherapy
- Reprogramming
- Biology
- Ovarian cancer
- Cancer
- Good health and well-being