reviewSignal Transduction and Targeted TherapyApr 18, 2024GOLD OA

Drug repurposing for cancer therapy

Guiyang College of Traditional Chinese Medicine · Johns Hopkins University · +5 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

Cancer, a complex and multifactorial disease, presents a significant challenge to global health. Despite significant advances in surgical, radiotherapeutic and immunological approaches, which have improved cancer treatment outcomes, drug therapy continues to serve as a key therapeutic strategy. However, the clinical efficacy of drug therapy is often constrained by drug resistance and severe toxic side effects, and thus there remains a critical need to develop novel cancer therapeutics. One promising strategy that has received widespread attention in recent years is drug repurposing: the identification of new applications for existing, clinically approved drugs. Drug repurposing possesses several inherent…

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