reviewGeroScienceApr 26, 2024HYBRID OA

Mitochondrial dysfunction in long COVID: mechanisms, consequences, and potential therapeutic approaches

TMTihamér MolnárALAndrea LehoczkiMFMónika FeketeRVRéka VárnaiLZLászló Závori

University of Pecs · Semmelweis University · +2 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has introduced the medical community to the phenomenon of long COVID, a condition characterized by persistent symptoms following the resolution of the acute phase of infection. Among the myriad of symptoms reported by long COVID sufferers, chronic fatigue, cognitive disturbances, and exercise intolerance are predominant, suggesting systemic alterations beyond the initial viral pathology. Emerging evidence has pointed to mitochondrial dysfunction as a potential underpinning mechanism contributing to the persistence and diversity of long COVID symptoms. This review aims to synthesize current findings related to mitochondrial dysfunction in long COVID,…

Citation impact

135
total citations
FWCI
44.82
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100%
References
170
Citations per year

Authors

10

Topics & keywords

Topics
Keywords
  • Coronavirus disease 2019 (COVID-19)
  • 2019-20 coronavirus outbreak
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
  • Virology
  • Medicine
  • Internal medicine
  • Infectious disease (medical specialty)
  • Disease
UN Sustainable Development Goals
  • Good health and well-being
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