articleInternational Journal of Molecular SciencesApr 29, 2024GOLD OA

The Role of Prebiotics in Modulating Gut Microbiota: Implications for Human Health

Incheon National University · University of Illinois Urbana-Champaign · +1 more institution

PubMed
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Abstract

The human gut microbiota, an intricate ecosystem within the gastrointestinal tract, plays a pivotal role in health and disease. Prebiotics, non-digestible food ingredients that beneficially affect the host by selectively stimulating the growth and/or activity of beneficial microorganisms, have emerged as a key modulator of this complex microbial community. This review article explores the evolution of the prebiotic concept, delineates various types of prebiotics, including fructans, galactooligosaccharides, xylooligosaccharides, chitooligosaccharides, lactulose, resistant starch, and polyphenols, and elucidates their impact on the gut microbiota composition. We delve into the mechanisms through which…

Citation impact

188
total citations
FWCI
56.09
Percentile
100%
References
108
Citations per year

Authors

4

Topics & keywords

Keywords
  • Gut flora
  • Human health
  • Biology
  • Prebiotic
  • Gut–brain axis
  • Computational biology
  • Medicine
  • Genetics
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