articleAnalytical ChemistryMay 9, 2024Closed access

Pt/Zn-TCPP Nanozyme-Based Flexible Immunoassay for Dual-Mode Pressure–Temperature Monitoring of Low-Abundance Proteins

Fuzhou University · Jiangxi Normal University · +2 more institutions

PubMed
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Abstract

Pressure and temperature, as common physical parameters, are important for monitoring human health. In contrast, single-mode monitoring is prone to causing experimental errors. Herein, we innovatively designed a dual-mode flexible sensing platform based on a platinum/zinc-meso-tetrakis(4-carboxyphenyl)porphyrin (Pt/Zn-TCPP) nanozyme for the quantitative monitoring of carcinoembryonic antigen (CEA) in biological fluids with pressure and temperature readouts. The Pt/Zn-TCPP nanozyme with catalytic and photothermal efficiencies was synthesized by means of integrating photosensitizers into porous materials. The flexible sensing system after the antigen–antibody reaction recognized the pressure using a flexible…

Citation impact

158
total citations
FWCI
17.14
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100%
References
30
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Authors

7

Topics & keywords

Keywords
  • Chemistry
  • Dual mode
  • Luminescence
  • Analyte
  • Optoelectronics
  • Chromatography
  • Materials science
  • Electronic engineering
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