articleNucleic Acids ResearchApr 23, 2024GOLD OA

ChIP-Atlas 3.0: a data-mining suite to explore chromosome architecture together with large-scale regulome data

Kyoto University · Kumamoto University · +2 more institutions

PubMed
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Abstract

ChIP-Atlas (https://chip-atlas.org/) presents a suite of data-mining tools for analyzing epigenomic landscapes, powered by the comprehensive integration of over 376 000 public ChIP-seq, ATAC-seq, DNase-seq and Bisulfite-seq experiments from six representative model organisms. To unravel the intricacies of chromatin architecture that mediates the regulome-initiated generation of transcriptional and phenotypic diversity within cells, we report ChIP-Atlas 3.0 that enhances clarity by incorporating additional tracks for genomic and epigenomic features within a newly consolidated 'annotation track' section. The tracks include chromosomal conformation (Hi-C and eQTL datasets), transcriptional regulatory elements…

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176
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Authors

3

Topics & keywords

Keywords
  • Epigenomics
  • Biology
  • Epigenome
  • Computational biology
  • Chromatin
  • Annotation
  • Genomics
  • Bioconductor
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