reviewChemical ReviewsMay 17, 2024HYBRID OA

Fluorescent Probes for Disease Diagnosis

Shandong Normal University · University of Bath · +5 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

. In this review, we describe current fluorescent probes designed for the detection and quantification of key bioactive molecules associated with common diseases, such as organ damage, inflammation, cancers, cardiovascular diseases, and brain disorders. We emphasize the strategies behind the design of fluorescent probes capable of disease biomarker detection and diagnosis and cover some aspects of combined diagnostic/therapeutic strategies based on regulating disease-related molecules. This review concludes with a discussion of the challenges and outlook for fluorescent probes, highlighting future avenues of research that should enable these probes to achieve accurate detection and identification of…

Citation impact

419
total citations
FWCI
69.97
Percentile
100%
References
263
Citations per year

Authors

13

Topics & keywords

Keywords
  • Disease
  • Biomarker
  • Identification (biology)
  • Computational biology
  • Diagnostic biomarker
  • Chemistry
  • Clinical diagnosis
  • Fluorescence
UN Sustainable Development Goals
  • Good health and well-being
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Funding