articleNature MedicineMay 17, 2024HYBRID OA

Dual-energy lattice-tip ablation system for persistent atrial fibrillation: a randomized trial

Fo Guang Shan · Assaf Harofeh Medical Center · +13 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

Clinical outcomes of catheter ablation for atrial fibrillation (AF) are suboptimal due, in part, to challenges in achieving durable lesions. Although focal point-by-point ablation allows for the creation of any required lesion set, this strategy necessitates the generation of contiguous lesions without gaps. A large-tip catheter, capable of creating wide-footprint ablation lesions, may increase ablation effectiveness and efficiency. In a randomized, single-blind, non-inferiority trial, 420 patients with persistent AF underwent ablation using a large-tip catheter with dual pulsed field and radiofrequency energies versus ablation using a conventional radiofrequency ablation system. The primary composite…

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131
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Authors

22

Topics & keywords

Keywords
  • Medicine
  • Ablation
  • Clinical endpoint
  • Atrial fibrillation
  • Catheter ablation
  • Randomized controlled trial
  • Cardiology
  • Surgery
UN Sustainable Development Goals
  • Affordable and clean energy
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