Recent Advancements in Bone Tissue Engineering: Integrating Smart Scaffold Technologies and Bio-Responsive Systems for Enhanced Regeneration
American University of Sharjah
Indexed incrossrefpubmed
Abstract
In exploring the challenges of bone repair and regeneration, this review evaluates the potential of bone tissue engineering (BTE) as a viable alternative to traditional methods, such as autografts and allografts. Key developments in biomaterials and scaffold fabrication techniques, such as additive manufacturing and cell and bioactive molecule-laden scaffolds, are discussed, along with the integration of bio-responsive scaffolds, which can respond to physical and chemical stimuli. These advancements collectively aim to mimic the natural microenvironment of bone, thereby enhancing osteogenesis and facilitating the formation of new tissue. Through a comprehensive combination of in vitro and in vivo studies, we…
Citation impact
146
total citations
- FWCI
- 24.53
- Percentile
- 100%
- References
- 197
Citations per year
Authors
3Topics & keywords
Topics
Keywords
- Scaffold
- Regeneration (biology)
- Tissue engineering
- Biocompatibility
- Nanotechnology
- Biomedical engineering
- Bone healing
- Biochemical engineering
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