reviewJournal of ChemistryMay 31, 2024GOLD OA

A Comprehensive Review of Free Radicals, Oxidative Stress, and Antioxidants: Overview, Clinical Applications, Global Perspectives, Future Directions, and Mechanisms of Antioxidant Activity of Flavonoid Compounds

SGSefren Geiner TumilaarAHAri HardiantoHDHirofumi DohiDKDikdik Kurnia

Padjadjaran University · Chiba University

Indexed incrossrefdoaj

Abstract

Absorption​ of free radicals in the body cannot be done by antioxidant compounds originating from the human body, so exogenous antioxidants are required to help in their natural antioxidant action. Oxidative stress can be caused by an imbalance of free radical inhibitors and the accumulation of free radicals that enter cellular structures. Synthetic antioxidants found in external antioxidants are not the primary choice because they are harmful and carcinogenic. Therefore, using natural ingredients provides a necessary alternative to constructing novel natural antioxidants. Recent studies have highlighted critical analysis and evaluation that flavonoids are a unique class of secondary metabolites found in…

Citation impact

196
total citations
FWCI
39.35
Percentile
100%
References
221
Citations per year

Authors

4

Topics & keywords

Topics
Keywords
  • Chemistry
  • Antioxidant
  • Radical
  • Flavonoid
  • Oxidative stress
  • Biochemistry
  • Biochemical engineering
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