EASL–EASD–EASO Clinical Practice Guidelines on the management of metabolic dysfunction-associated steatotic liver disease (MASLD): Executive Summary

Metabolic dysfunction-associated steatotic liver disease (MASLD), previously termed non-alcoholic fatty liver disease (NAFLD), is defined as steatotic liver disease (SLD) in the presence of one or more cardiometabolic risk factor(s) and the absence of harmful alcohol intake. The spectrum of MASLD includes steatosis, metabolic dysfunction-associated steatohepatitis (MASH, previously NASH), fibrosis, cirrhosis and MASH-related hepatocellular carcinoma (HCC). This joint EASL-EASD-EASO guideline provides an update on definitions, prevention, screening, diagnosis and treatment for MASLD. Case-finding strategies for MASLD with liver fibrosis, using non-invasive tests, should be applied in individuals with…

• UD
  Università degli Studi di Milano
• HD
  Heinrich-Heine-Universität Düsseldorf
• CU
  Chinese University of Hong Kong
• UO
  University of Haifa
• UD
  Università degli Studi di Torino
• EA
  European Association for the Study of Diabetes
• EA
  European Association for the Study of the Liver
• FI
  Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
• SU
  Sorbonne Université
• L
  Leibniz-Gemeinschaft
• ID
  Institut de Cardiométabolisme et Nutrition