articleCirculationJun 17, 2024GREEN OA

Advanced Cardiac Patches for the Treatment of Myocardial Infarction

Sichuan University · West China Hospital of Sichuan University

PubMed
Indexed incrossrefpubmed

Abstract

Myocardial infarction is a cardiovascular disease characterized by a high incidence rate and mortality. It leads to various cardiac pathophysiological changes, including ischemia/reperfusion injury, inflammation, fibrosis, and ventricular remodeling, which ultimately result in heart failure and pose a significant threat to global health. Although clinical reperfusion therapies and conventional pharmacological interventions improve emergency survival rates and short-term prognoses, they are still limited in providing long-lasting improvements in cardiac function or reversing pathological progression. Recently, cardiac patches have gained considerable attention as a promising therapy for myocardial infarction.…

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