Organic fertilization co-selects genetically linked antibiotic and metal(loid) resistance genes in global soil microbiome
East China Normal University · Chinese Academy of Sciences · +3 more institutions
Abstract
Antibiotic resistance genes (ARGs) and metal(loid) resistance genes (MRGs) coexist in organic fertilized agroecosystems based on their correlations in abundance, yet evidence for the genetic linkage of ARG-MRGs co-selected by organic fertilization remains elusive. Here, an analysis of 511 global agricultural soil metagenomes reveals that organic fertilization correlates with a threefold increase in the number of diverse types of ARG-MRG-carrying contigs (AMCCs) in the microbiome (63 types) compared to non-organic fertilized soils (22 types). Metatranscriptomic data indicates increased expression of AMCCs under higher arsenic stress, with co-regulation of the ARG-MRG pairs. Organic fertilization heightens the…
Citation impact
- FWCI
- 14.63
- Percentile
- 100%
- References
- 80
Authors
6- ZLZiteng LiuCorresponding
East China Normal University
- RMRui-Ao Ma
East China Normal University
- DZDong Zhu
Chinese Academy of Sciences, Institute of Urban Environment
- KTKonstantinos T. Konstantinidis
Georgia Institute of Technology
- YZYong‐Guan Zhu
Chinese Academy of Sciences, Institute of Urban Environment, Research Center for Eco-Environmental Sciences
Topics & keywords
- Biology
- Metagenomics
- Microbiome
- Genome
- Gene
- Mobile genetic elements
- Genetics
- Biotechnology
- Zero hunger