Advances in spatial transcriptomics and its applications in cancer research

Malignant tumors have increasing morbidity and high mortality, and their occurrence and development is a complicate process. The development of sequencing technologies enabled us to gain a better understanding of the underlying genetic and molecular mechanisms in tumors. In recent years, the spatial transcriptomics sequencing technologies have been developed rapidly and allow the quantification and illustration of gene expression in the spatial context of tissues. Compared with the traditional transcriptomics technologies, spatial transcriptomics technologies not only detect gene expression levels in cells, but also inform the spatial location of genes within tissues, cell composition of biological tissues,…

• NN
  National Natural Science Foundation of China

  Award: 32100524
• SU
  Sichuan University
• WC
  West China Hospital, Sichuan University

  Awards: ZYGD23027, 1.3.5