articleSignal Transduction and Targeted TherapyJul 1, 2024GOLD OA

Harnessing the potential of hydrogels for advanced therapeutic applications: current achievements and future directions

Sun Yat-sen University · Second Affiliated Hospital of Guangzhou Medical University · +6 more institutions

PubMed
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Abstract

The applications of hydrogels have expanded significantly due to their versatile, highly tunable properties and breakthroughs in biomaterial technologies. In this review, we cover the major achievements and the potential of hydrogels in therapeutic applications, focusing primarily on two areas: emerging cell-based therapies and promising non-cell therapeutic modalities. Within the context of cell therapy, we discuss the capacity of hydrogels to overcome the existing translational challenges faced by mainstream cell therapy paradigms, provide a detailed discussion on the advantages and principal design considerations of hydrogels for boosting the efficacy of cell therapy, as well as list specific examples of…

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