Biomarker-driven molecular imaging probes in radiotherapy
Sichuan University · West China Hospital of Sichuan University · +2 more institutions
Abstract
Background: Biomarker-driven molecular imaging has emerged as an integral part of cancer precision radiotherapy.The use of molecular imaging probes, including nanoprobes, have been explored in radiotherapy imaging to precisely and noninvasively monitor spatiotemporal distribution of biomarkers, potentially revealing tumor-killing mechanisms and therapy-induced adverse effects during radiation treatment.Methods: We summarized literature reports from preclinical studies and clinical trials, which cover two main parts: 1) Clinically-investigated and emerging imaging biomarkers associated with radiotherapy, and 2) instrumental roles, functions, and activatable mechanisms of molecular imaging probes in the…
Citation impact
- FWCI
- 41.37
- Percentile
- 100%
- References
- 202
Authors
3- HLHaonan LiCorresponding
Sichuan University, West China Hospital of Sichuan University
- QGQiyong Gong
Jimei University, Chinese Academy of Medical Sciences & Peking Union Medical College, Sichuan University, West China Hospital of Sichuan University
- KLKui Luo
Chinese Academy of Medical Sciences & Peking Union Medical College, Sichuan University, West China Hospital of Sichuan University
Topics & keywords
- Biomarker
- Molecular imaging
- Radiation therapy
- Imaging biomarker
- Medicine
- Medical physics
- Magnetic resonance imaging
- Radiology
Funding
- NNNational Natural Science Foundation of ChinaAwards: 52073193, 81621003, 51873120, ZYJC21013
- DODepartment of Science and Technology of Sichuan ProvinceAwards: 51873120, 2024NSFJQ0050, ZYJC21013, 52073193, 81621003
- SUSichuan UniversityAwards: ZYJC21013, 51873120, 52073193, 81621003
- WCWest China Hospital, Sichuan UniversityAwards: 81621003, 52073193, ZYJC21013, 51873120