Sleep patterns and risk of chronic disease as measured by long-term monitoring with commercial wearable devices in the All of Us Research Program

Poor sleep health is associated with increased all-cause mortality and incidence of many chronic conditions. Previous studies have relied on cross-sectional and self-reported survey data or polysomnograms, which have limitations with respect to data granularity, sample size and longitudinal information. Here, using objectively measured, longitudinal sleep data from commercial wearable devices linked to electronic health record data from the All of Us Research Program, we show that sleep patterns, including sleep stages, duration and regularity, are associated with chronic disease incidence. Of the 6,785 participants included in this study, 71% were female, 84% self-identified as white and 71% had a college…

• G
  Google
• NI
  National Institutes of Health

  Awards: OD026553, 3 OT2 OD025315, OT2 OD026551, U24 OD023121, 3 OT2 OD023206, 1 OT2 OD025276, 1 U24 OD023121, OT2 OD025277, OT2 OD025315, 1 OT2 OD026549, OT2 OD026557, 1 OT2 OD026551, AOD21041, 1 OT2 OD026550, 1 OT2 OD 026552, U2C OD023196, OT2 OD 026552, OT2 OD026553, 3 OT2 OD023205, 1 OT2 OD026554, 1 OT2 OD025337, OT2 OD023206, AOD22003, OT2 OD026554, OT2 OD026556, OT2 OD026550, OT2 OD026548, OT2 OD026555, 1 OT2 OD026548, 1 OT2 OD026555, OT2 OD026549, OT2 OD025337, U24 OD023163, 1 OT2 OD026557, 1 OT2 OD026553, 1 OT2 OD025277, OT2 OD025276, AOD16037, U24 OD023176, 5 U2C OD023196, 1 OT2 OD026556, HHSN 263201600085U, 263201600085U, OT2 OD023205
• UF
  U.S. Food and Drug Administration

  Award: FD007627
• NH
  National Heart, Lung, and Blood Institute

  Awards: HL158941, HL172038