reviewAdvanced Healthcare MaterialsJul 22, 2024Closed access

Chitosan‐Based Hydrogels as Antibacterial/Antioxidant/Anti‐Inflammation Multifunctional Dressings for Chronic Wound Healing

China-Japan Friendship Hospital · Sichuan University · +1 more institution

PubMed
Indexed incrossrefpubmed

Abstract

Due to repeated microbial infection, persistent inflammation, excessive oxidative stress, and cell dysfunction, chronic wounds are difficult to heal, posing a serious threat to public health. Therefore, developing multifunctional wound dressings that can regulate the complex microenvironment of chronic wounds and enhance cellular function holds great significance. Recently, chitosan has emerged as a promising biopolymer for wound healing due to its excellent biocompatibility, biodegradability, and versatile bioactivity. The aim of this review is to provide a comprehensive understanding of the mechanisms of delayed chronic wound healing and discuss the healing-promoting properties of chitosan and its…

Citation impact

123
total citations
FWCI
27.98
Percentile
100%
References
164
Citations per year

Authors

4

Topics & keywords

Keywords
  • Wound healing
  • Biocompatibility
  • Self-healing hydrogels
  • Chitosan
  • Regeneration (biology)
  • Oxidative stress
  • Inflammation
  • Chronic wound
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