Exploring the Gut Microbiota: Key Insights Into Its Role in Obesity, Metabolic Syndrome, and Type 2 Diabetes
University of Southern California · Children's Hospital of Los Angeles · +1 more institution
Abstract
The gut microbiota (GM), comprising trillions of microorganisms in the gastrointestinal tract, is a key player in the development of obesity and related metabolic disorders, such as type 2 diabetes (T2D), metabolic syndrome (MS), and cardiovascular diseases. This mini-review delves into the intricate roles and mechanisms of the GM in these conditions, offering insights into potential therapeutic strategies targeting the microbiota. The review elucidates the diversity and development of the human GM, highlighting its pivotal functions in host physiology, including nutrient absorption, immune regulation, and energy metabolism. Studies show that GM dysbiosis is linked to increased energy extraction, altered…
Citation impact
- FWCI
- 24.06
- Percentile
- 100%
- References
- 121
Authors
4Topics & keywords
- Gut flora
- Dysbiosis
- Type 2 diabetes
- Metabolic syndrome
- Biology
- Obesity
- Fecal bacteriotherapy
- Immune system