Gut microbiota metabolite indole-3-acetic acid maintains intestinal epithelial homeostasis through mucin sulfation
Tianjin Medical University General Hospital · Nankai University · +2 more institutions
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Abstract
) and the ability to produce IAA fail to exhibit such effects. Overall, IAA enhances intestinal mucin sulfation through the AHR-Papss2-Slc35b3 pathway, contributing to the protection of intestinal homfeostasis.
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115
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18Topics & keywords
Topics
Keywords
- Mucin
- Colitis
- Sulfation
- Biology
- Gut flora
- Biochemistry
- Lactobacillus reuteri
- Inflammatory bowel disease
UN Sustainable Development Goals
- Zero hunger
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