reviewMetabolic Brain DiseaseJul 31, 2024HYBRID OA

Stress, hypothalamic-pituitary-adrenal axis, hypothalamic-pituitary-gonadal axis, and aggression

Stellenbosch University · Copperbelt University

PubMed
Indexed incrossrefpubmed

Abstract

This comprehensive review explores the intricate relationship between the hypothalamic-pituitary-adrenal (HPA) axis, the hypothalamic-pituitary-gonadal (HPG) axis, and aggression. It provides a detailed overview of the physiology and functioning of these axes, as well as the implications for aggressive behavior. The HPA axis, responsible for the stress response, is activated in response to various stressors and can influence aggressive behavior. Glucocorticoids, such as cortisol, play a crucial role in stress-induced activation of the HPA axis and have been implicated in aggressive tendencies. Chronic stress can dysregulate the HPA axis, leading to alterations in cortisol levels and potentially contributing to…

Citation impact

192
total citations
FWCI
51.35
Percentile
100%
References
155
Citations per year

Authors

2

Topics & keywords

Keywords
  • Aggression
  • Hypothalamic–pituitary–gonadal axis
  • Psychology
  • Hypothalamic–pituitary–adrenal axis
  • Neuroscience
  • Testosterone (patch)
  • Androgen
  • Endocrinology
UN Sustainable Development Goals
  • Good health and well-being
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