reviewGut PathogensAug 3, 2024GOLD OA

The influence of Akkermansia muciniphila on intestinal barrier function

Kunming University of Science and Technology · First People's Hospital of Yunnan Province

PubMed
Indexed incrossrefdoajpubmed

Abstract

Intestinal barriers play a crucial role in human physiology, both in homeostatic and pathological conditions. Disruption of the intestinal barrier is a significant factor in the pathogenesis of gastrointestinal inflammatory diseases, such as inflammatory bowel disease. The profound influence of the gut microbiota on intestinal diseases has sparked considerable interest in manipulating it through dietary interventions, probiotics, and fecal microbiota transplantation as potential approaches to enhance the integrity of the intestinal barrier. Numerous studies have underscored the protective effects of specific microbiota and their associated metabolites. In recent years, an increasing body of research has…

Citation impact

158
total citations
FWCI
33.34
Percentile
100%
References
126
Citations per year

Authors

7

Topics & keywords

Keywords
  • Akkermansia muciniphila
  • Barrier function
  • Gut flora
  • Medicine
  • Akkermansia
  • Biology
  • Immunology
  • Lactobacillus
UN Sustainable Development Goals
  • Good health and well-being
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