Enhancing wound healing and minimizing scarring: A comprehensive review of nanofiber technology in wound dressings

Wound healing is a complex biological process that, when impaired, can lead to the formation of scars. Electrospun nanofibrous wound dressings have emerged as a promising option for promoting scar-free wound healing. This paper explores the complex role of physical, compositional, and chemical cues, each contributing to the remarkable healing potential of these wound dressings. The physical properties of these dressings, such as porosity and mechanical characteristics, can guide cellular behaviors and promote vascularization, fostering a conducive environment for reduced scarring. Furthermore, the integration of natural polymers that mimic the skin’s extracellular matrix, known as compositional cues, adds…

• UO
  University of Manitoba

  Award: 7889807
• NS
  Natural Sciences and Engineering Research Council of Canada

  Award: RGPIN-2019-06094