Cell–cell communication: new insights and clinical implications

Multicellular organisms are composed of diverse cell types that must coordinate their behaviors through communication. Cell-cell communication (CCC) is essential for growth, development, differentiation, tissue and organ formation, maintenance, and physiological regulation. Cells communicate through direct contact or at a distance using ligand-receptor interactions. So cellular communication encompasses two essential processes: cell signal conduction for generation and intercellular transmission of signals, and cell signal transduction for reception and procession of signals. Deciphering intercellular communication networks is critical for understanding cell differentiation, development, and metabolism. First,…

• NN
  National Natural Science Foundation of China

  Awards: 82300433, 32170656
• PU
  Peking University
• PU
  Peking University Third Hospital
• BM
  Beijing Municipal Science and Technology Commission

  Award: 7224348
• BN
  Beijing Nova Program

  Award: Z211100002121039