Spatial multi-omics: deciphering technological landscape of integration of multi-omics and its applications
Union Hospital · Tongji Hospital · +3 more institutions
Abstract
The emergence of spatial multi-omics has helped address the limitations of single-cell sequencing, which often leads to the loss of spatial context among cell populations. Integrated analysis of the genome, transcriptome, proteome, metabolome, and epigenome has enhanced our understanding of cell biology and the molecular basis of human diseases. Moreover, this approach offers profound insights into the interactions between intracellular and intercellular molecular mechanisms involved in the development, physiology, and pathogenesis of human diseases. In this comprehensive review, we examine current advancements in multi-omics technologies, focusing on their evolution and refinement over the past decade,…
Citation impact
- FWCI
- 27.50
- Percentile
- 100%
- References
- 158
Authors
12- XLXiaojie LiuCorresponding
Union Hospital, Tongji Hospital, Huazhong University of Science and Technology
- TPTing Peng
Union Hospital, Tongji Hospital, Huazhong University of Science and Technology
- MXMiaochun Xu
Union Hospital, Tongji Hospital, Huazhong University of Science and Technology
- SLShitong Lin
Union Hospital, Tongji Hospital, Huazhong University of Science and Technology
- BHBai Hu
Tongji Hospital, Huazhong University of Science and Technology
Topics & keywords
- Epigenome
- Omics
- Computational biology
- Metabolome
- Biology
- Context (archaeology)
- Transcriptome
- Exposome