reviewStem Cell Research & TherapyAug 26, 2024GOLD OA

Translational potential of mesenchymal stem cells in regenerative therapies for human diseases: challenges and opportunities

Second Affiliated Hospital of Jilin University · Union Hospital · +1 more institution

PubMed
Indexed incrossrefdoajpubmed

Abstract

Advances in stem cell technology offer new possibilities for patients with untreated diseases and disorders. Stem cell-based therapy, which includes multipotent mesenchymal stem cells (MSCs), has recently become important in regenerative therapies. MSCs are multipotent progenitor cells that possess the ability to undergo in vitro self-renewal and differentiate into various mesenchymal lineages. MSCs have demonstrated promise in several areas, such as tissue regeneration, immunological modulation, anti-inflammatory qualities, and wound healing. Additionally, the development of specific guidelines and quality control methods that ultimately result in the therapeutic application of MSCs has been made easier by…

Citation impact

137
total citations
FWCI
53.37
Percentile
100%
References
244
Citations per year

Authors

4

Topics & keywords

Keywords
  • Mesenchymal stem cell
  • Stem cell
  • Regenerative medicine
  • Regeneration (biology)
  • Medicine
  • Stem-cell therapy
  • Multipotent Stem Cell
  • Progenitor cell
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