A smart mask for exhaled breath condensate harvesting and analysis

Recent respiratory outbreaks have garnered substantial attention, yet most respiratory monitoring remains confined to physical signals. Exhaled breath condensate (EBC) harbors rich molecular information that could unveil diverse insights into an individual's health. Unfortunately, challenges related to sample collection and the lack of on-site analytical tools impede the widespread adoption of EBC analysis. Here, we introduce EBCare, a mask-based device for real-time in situ monitoring of EBC biomarkers. Using a tandem cooling strategy, automated microfluidics, highly selective electrochemical biosensors, and a wireless reading circuit, EBCare enables continuous multimodal monitoring of EBC analytes across…

• NS
  National Science Foundation

  Award: 2145802
• TD
  Tobacco-Related Disease Research Program

  Award: T31IP1666
• CI
  California Institute of Technology
• NI
  National Institutes of Health

  Awards: R01HL155815, R21DK13266
• KN
  Kavli Nanoscience Institute, California Institute of Technology
• OO
  Office of Naval Research

  Awards: N00014-21-1-2845, T31IP1666, N00014-21-1-2483, N00014
• DO
  Division of Materials Research
• AR
  Army Research Office

  Awards: W911NF-23-1-0041, W911NF
• UA
  U.S. Army Medical Research Acquisition Activity

  Award: HT9425-24-1-0249