articleThe American Journal of GastroenterologySep 1, 2024Closed access

ACG Clinical Guideline: Treatment of Helicobacter pylori Infection

Michigan Medicine · University of Tennessee Health Science Center · +9 more institutions

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Abstract

ABSTRACT: Helicobacter pylori is a prevalent, global infectious disease that causes dyspepsia, peptic ulcer disease, and gastric cancer. The American College of Gastroenterology commissioned this clinical practice guideline (CPG) to inform the evidence-based management of patients with H. pylori infection in North America. This CPG used Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) methodology to systematically analyze 11 Population, Intervention, Comparison, and Outcome questions and generate recommendations. Where evidence was insufficient or the topic did not lend itself to GRADE, expert consensus was used to create 6 key concepts. For treatment-naive patients with H. pylori…

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