Neoadjuvant pembrolizumab plus chemotherapy followed by adjuvant pembrolizumab compared with neoadjuvant chemotherapy alone in patients with early-stage non-small-cell lung cancer (KEYNOTE-671): a randomised, double-blind, placebo-controlled, phase 3 trial

Spicer, Jonathan; Garassino, Marina Chiara; Wakelee, Heather A.; Liberman, Moïshe; Kato, Terufumi; Tsuboi, Masahiro; Lee, Se‐Hoon; Chen, Ke‐Neng; Dooms, Christophe; Majem, Margarita; Eigendorff, E.; Martinengo, Gastón Lucas; Bylicki, Olivier; Rodríguez‐Abreu, Delvys; Chaft, Jamie E.; Novello, Silvia; Yang, Jing; Arunachalam, Ashwini; Keller, Steven M.; Samkari, Ayman; Gao, Shugeng; Afanasyev, Sergey; Ahmed, Samreen; Alekshun, Todd; Alves, Gustavo; Anderson, Ian; Araujo, Luiz Henrique; Arkhipov, Alexander; Arora, Arvind; Bai, Jie; Begin, Paul; Belonogov, Aleksandr; Berard, Henri; Berceanu-Ion, Radu; Caro, Reyes Bernabe; Bondarenko, Igor; Bonnet, Reiner; Barrera, Joaquim Bosch; Brocca, Carlos; Bryl, Maciej; Bulotta, Alessandra; Bylicki, Olivier; Blanco, Antonio Calles; Carcereny, Enric; Carvalho, Leticia; Cebotaru, Cristina; Chaft, Jamie; Charu, Veena; Chaves, Fabio; Chen, Jun; Chen, Ke-Neng; Chen, Haiquan; Chen, Qixun; Chen, Kevin; Chiang, Chi-Lu; Chiu, Chao-Hua; Cicenas, Saulius; Ciubotaru, Elena; Ciuleanu, Tudor; Ciurescu, Ioana; Cobb, Patrick; Coetzee, Corlia; Collins, Dearbhaile; Cortinovis, Diego; Costas, Kimberly; Costin, Dan; Cronemberger, Eduardo Henrique; Cuevo, Raymund; Cuffe, Sinead; Marchi, Pedro Rafael Martins De; Junior, Tadeu de Paiva; Delmonte, Angelo; Demedts, Ingel; Deschepper, Koenraad; Dias, Josiane; Dooms, Christophe; Duchemann, Boris; Dutra, Carolina; Duvivier, Herbert; Eigendorff, Ekkehard; Ernani, Vinicius; Faehling, Martin; Faria, Luiza; Fedenko, Alexander; Fernando, Hiran; Ferrara, Roberto; Ferrari, Vittorio; Finley, Gene; Fix, Peter; Flores, Marcos; Fourie, Samuel; Franke, Fabio; Frohling, Klaus-Peter; Furqan, Muhammad; Gal, Cristian; Galamaga, Robert; Ganea, Doina; Ganti, Apar Kishor; Gao, Shugeng; Garassino, Marina; Gentzler, Ryan; Gianni, Luca; Gilli, Marina; Girard, Nicolas; Goranov, Bojidar; Gregorc, Vanesa; Greystoke, Alastair; Grisanti, Salvatore; Grohe, Christian; Guarino, Michael; Guimaraes, Jose Luiz; Guisier, Florian; Halmos, Balazs; Hammoud, Zane Taysir; Han, Ji-Youn; Hegmane, Alinta; Heng, Fook Yew; Horinouchi, Hidehito; Horio, Yoshitsugu; Hu, Jian; Huang, Hsu-Ching; Hui, Rina; Ikeda, Norihiko; Intagliata, Salvatore; Iordan, Ingrid; Jacobs, Conrad; Jain, Kirti; Jain, Sushil; Jiang, Tao; Karaseva, Nina; Kato, Terufumi; Kaywin, Paul; Kazmi, Shayma; Keresztes, Roger; Khan, Sarah; Kim, Jhingook; Kolesnik, Olena; Kolesnik, Oleksii; Kollmeier, Jens; Komiya, Takefumi; Koontz, Michael; Krasnohrud, Yuliia; Kristedja, Timothy; Kryzhanivska, Anna; Kuroda, Hiroaki; Laktionov, Konstantin; Lambrechts, Marc; Lang, Susanne; Langleben, Adrian; Lee, Se-Hoon; Lehmann, Markus; Levchenko, Evgeny; Levenko, Oleh; Li, Shanqing; Liao, Bin-Chi; Liberman, Moishe; Lima, Iane; Liu, Geoffrey; Liu-Dumlao, Theresa; Russo, Giuseppe Lo; Lou, Yan Yan; Lowczak, Anna; Luft, Alexander; Ma, Shaohua; Tarruella, Margarita Majem; Makles, Krytsyna; Martinengo, Gaston; Marti, Alex Martinez; Matias, Danielli; Mazieres, Julien; Mazilu, Laura; Mennecier, Bertrand; Migliorino, Maria Rita; Misleh, Jamal; Molina, Julian; Morbeck, Igor; Mueller, Annette; Muto, Satoshi; Alforja, Ernest Nadal; Nesterova, Alfiya; Nishio, Wataru; Niu, Jiaxin; Novello, Silvia; O'Brien, Mary; O'Day, Steven; Ogliari, Francesca; Okada, Morihito; Pang, Yong Kek; Paramonov, Viktor; Pastor, Andrea; Pawlak, Ireneusz; Piantedosi, Francovito; Pollock, Theodore; Pope, Tony; Puig, Juan; Radhi, Saba; Rao, Suman; Rathnasabapathy, Chenthilmurugan; Reck, Martin; Reinacher-Schick, Anke; Rich, Patricia; Ritgen, Mathias; Rittmeyer, Achim; Roca, Elisa; Rodriguez-Abreu, Delvys; Ruff, Paul; Rybkin, Igor; Saji, Hisashi; Sakao, Yukinori; Sangal, Ashish; Santoro, Armando; Sardenberg, Rodrigo; Savvides, Panayiotis; Scheusan, Roxana; Schiller, Joan; Schumacher, Lana; Serke, Monika; Shim, Byoung Yong; Shimizu, Junichi; Shio, Yutaka; Sibille, Anne; Siegel, Robert; Signorelli, Diego; Smagina, Maria; Sokur, Iryna; Spicer, Jonathan; Srkalovic, Gordan; Stampleman, Laura; Starodub, Alexander; Stencel, Katarzyna; Sugio, Kenji; Surmont, Veerle; Suzuki, Hiroyuki; Tabacof, Jacques; Takamochi, Kazuya; Tan, Lijie; Tanaka, Fumihiro; Tatangelo, Marcelo; Täuscher, Dagmar; Teixeira, Carlos; Thiberville, Luc; Trukhin, Dmytro; Tsai, Chen-Liang; Tsuboi, Masahiro; Ungureanu, Andrei; Ursol, Grygorii; Vanakesa, Tonu; Vansteenkiste, Johan; Varela, Mirta; Villalona-Calero, Miguel; Villaruz, Liza; Vogel, Gunther; Voitko, Nataliia; Wakelee, Heather; Wang, Qun; Wang, Wenxiang; Wang, Chin-Chou; Wang, Sarah; Wehler, Thomas; Weksler, Benny; Wermke, Martin; Wesseler, Claas; Wirtz, Hubert; Wong, Mark; Yan, Xiaolong; Yang, Yue; Yu, Kong Leong; Zasadny, Xavier; Zemaitis, Marius; Zhang, Lanjun; Zhao, Guofang; Zhao, Qing; Zhu, Yuming; Zurawski, Bogdan

doi:10.1016/s0140-6736(24)01756-2

articleThe LancetSep 1, 2024GREEN OA

Neoadjuvant pembrolizumab plus chemotherapy followed by adjuvant pembrolizumab compared with neoadjuvant chemotherapy alone in patients with early-stage non-small-cell lung cancer (KEYNOTE-671): a randomised, double-blind, placebo-controlled, phase 3 trial

JSJonathan Spicer MCMarina Chiara Garassino HAHeather A. Wakelee MLMoïshe Liberman TKTerufumi Kato

University of Chicago · Kanagawa Prefectural Hospital Organization · +16 more institutions

PubMed

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Topics & keywords

Topics

Keywords

Pembrolizumab
Medicine
Chemotherapy
Oncology
Stage (stratigraphy)
Internal medicine
Lung cancer
Adjuvant

UN Sustainable Development Goals

Good health and well-being

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