reviewMedCommSep 15, 2024GOLD OA

The interaction of innate immune and adaptive immune system

Tongji Hospital · Huazhong University of Science and Technology · +15 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

The innate immune system serves as the body's first line of defense, utilizing pattern recognition receptors like Toll-like receptors to detect pathogens and initiate rapid response mechanisms. Following this initial response, adaptive immunity provides highly specific and sustained killing of pathogens via B cells, T cells, and antibodies. Traditionally, it has been assumed that innate immunity activates adaptive immunity; however, recent studies have revealed more complex interactions. This review provides a detailed dissection of the composition and function of the innate and adaptive immune systems, emphasizing their synergistic roles in physiological and pathological contexts, providing new insights into…

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