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reviewnpj Science of FoodSep 18, 2024GOLD OA

RETRACTED ARTICLE: Recent advances and challenges in single cell protein (SCP) technologies for food and feed production

YPYu Pin LiFAFatemeh AhmadiKKKhalil KarimanMLMaximilian Lackner

Yunnan Agricultural University · The University of Western Australia · +1 more institution

PubMed
Indexed incrossrefdoajpubmed

Abstract

The global population is increasing, with a predicted demand for 1250 million tonnes of animal-derived protein by 2050, which will be difficult to meet. Single-cell protein (SCP) offers a sustainable solution. This review covers SCP production mechanisms, microbial and substrate choices, and advancements in metabolic engineering and CRISPR-Cas. It emphasizes second-generation substrates and fermentation for a circular economy. Despite challenges like high nucleic acid content, SCP promises to solve the global nutrition problem.

Citation impact

112
total citations
FWCI
23.63
Percentile
100%
References
192
Citations per year

Authors

4

Topics & keywords

Topics
Keywords
  • Single-cell protein
  • Production (economics)
  • Population
  • CRISPR
  • Global population
  • Fermentation
  • Biochemical engineering
  • Biotechnology
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