Antimicrobial resistance: a concise update

Antimicrobial resistance (AMR) is a serious threat to global public health, with approximately 5 million deaths associated with bacterial AMR in 2019. Tackling AMR requires a multifaceted and cohesive approach that ranges from increased understanding of mechanisms and drivers at the individual and population levels, AMR surveillance, antimicrobial stewardship, improved infection prevention and control measures, and strengthened global policies and funding to development of novel antimicrobial therapeutic strategies. In this rapidly advancing field, this Review provides a concise update on AMR, encompassing epidemiology, evolution, underlying mechanisms (primarily those related to last-line or newer generation…

• IF
  Impact Fund
• UO
  University of Pennsylvania
• UT
  United Therapeutics Corporation
• NI
  National Institute for Health and Care Research

  Awards: NIHR203326, II-LA-1117-20001
• EC
  European Commission

  Award: 739593
• KT
  Killam Trusts
• NI
  National Institutes of Health

  Awards: -0001, R35GM138201
• PS
  Perelman School of Medicine, University of Pennsylvania
• MR
  Medical Research Council

  Awards: MR/X019195/1, MR/T001674/1, MR/T001674/1, MR/N019016/1, MR/X502996/1
• IF
  Invention for Innovation

  Award: II-LA-1117-20001
• BB
  Birmingham Biomedical Research Centre

  Award: NIHR203326
• NI
  National Institute of General Medical Sciences

  Award: R35GM138201