What defines a healthy gut microbiome?
Walloon Excellence in Lifesciences and Biotechnology · UCLouvain · +4 more institutions
Abstract
The understanding that changes in microbiome composition can influence chronic human diseases and the efficiency of therapies has driven efforts to develop microbiota-centred therapies such as first and next generation probiotics, prebiotics and postbiotics, microbiota editing and faecal microbiota transplantation. Central to microbiome research is understanding how disease impacts microbiome composition and vice versa, yet there is a problematic issue with the term 'dysbiosis', which broadly links microbial imbalances to various chronic illnesses without precision or definition. Another significant issue in microbiome discussions is defining 'healthy individuals' to ascertain what characterises a healthy…
Citation impact
- FWCI
- 59.37
- Percentile
- 100%
- References
- 195
Authors
6- MVMatthias Van Hul
Walloon Excellence in Lifesciences and Biotechnology, UCLouvain
- PDPatrice D. CaniCorresponding
Walloon Excellence in Lifesciences and Biotechnology, UCLouvain
- CPCamille Petitfils
Walloon Excellence in Lifesciences and Biotechnology, UCLouvain
- WMWillem M. de Vos
University of Helsinki, Wageningen University & Research
- HTHerbert Tilg
Innsbruck Medical University
Topics & keywords
- Microbiome
- Dysbiosis
- Gut microbiome
- Population
- Disease
- Gut flora
- Medicine
- Immunology
Funding
- AGAustralian Government
- FDFonds De La Recherche Scientifique - FNRSAwards: T.0030.21, FNRS T.0030.21, WELBIO-CR-2022A-02P, EOS: program no. 40007505, 40007505
- NONederlandse Organisatie voor Wetenschappelijk OnderzoekAward: 024.002.002
- BFBundesministerium für Verkehr, Innovation und Technologie
- ADAttorney-General's Department, Australian GovernmentAward: Grant No EPCD000026
- BFBusiness FinlandAward: 329/31/2015
- WEWalloon excellence in life sciences and biotechnology