reviewEuropean Heart JournalSep 26, 2024GREEN OA

Cardiovascular care with digital twin technology in the era of generative artificial intelligence

Yale University · Amsterdam University Medical Centers · +5 more institutions

PubMed
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Abstract

Digital twins, which are in silico replications of an individual and its environment, have advanced clinical decision-making and prognostication in cardiovascular medicine. The technology enables personalized simulations of clinical scenarios, prediction of disease risk, and strategies for clinical trial augmentation. Current applications of cardiovascular digital twins have integrated multi-modal data into mechanistic and statistical models to build physiologically accurate cardiac replicas to enhance disease phenotyping, enrich diagnostic workflows, and optimize procedural planning. Digital twin technology is rapidly evolving in the setting of newly available data modalities and advances in generative…

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