CRISPR-Cas9-mediated homology-directed repair for precise gene editing
Sichuan University · West China Second University Hospital of Sichuan University · +1 more institution
Indexed incrossrefdoajpubmed
Abstract
Gene therapies. Finally, we discuss alternative precise editing platforms and their limitations, and describe potential avenues to improving CRISPR-Cas9-mediated HDR efficiency and fidelity in future research.
Citation impact
113
total citations
- FWCI
- 23.85
- Percentile
- 100%
- References
- 227
Citations per year
Authors
5- HLHongyu LiaoCorresponding
Sichuan University, West China Second University Hospital of Sichuan University
- JWJiahao Wu
Sichuan University, West China Second University Hospital of Sichuan University
- NJNathan J. VanDusen
Indiana University – Purdue University Indianapolis
- YLYifei Li
Sichuan University, West China Second University Hospital of Sichuan University
- YZYanjiang Zheng
Sichuan University, West China Second University Hospital of Sichuan University
Topics & keywords
Topics
Keywords
- CRISPR
- Genome editing
- Genetics
- Gene
- Biology
- Homology (biology)
- Computational biology
- Homology directed repair
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