reviewBiomarker ResearchSep 27, 2024GOLD OA

Single-cell sequencing to multi-omics: technologies and applications

XWXiangyu WuXYXin YangYDYunhan DaiZZZihan ZhaoJZJunmeng Zhu

Nanjing Drum Tower Hospital · Nanjing Medical University · +1 more institution

PubMed
Indexed incrossrefdoajpubmed

Abstract

Cells, as the fundamental units of life, contain multidimensional spatiotemporal information. Single-cell RNA sequencing (scRNA-seq) is revolutionizing biomedical science by analyzing cellular state and intercellular heterogeneity. Undoubtedly, single-cell transcriptomics has emerged as one of the most vibrant research fields today. With the optimization and innovation of single-cell sequencing technologies, the intricate multidimensional details concealed within cells are gradually unveiled. The combination of scRNA-seq and other multi-omics is at the forefront of the single-cell field. This involves simultaneously measuring various omics data within individual cells, expanding our understanding across a…

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144
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30.39
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100%
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250
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Authors

7

Topics & keywords

Topics
Keywords
  • Omics
  • Computational biology
  • Transcriptome
  • Single cell sequencing
  • Computer science
  • Data science
  • Biology
  • Bioinformatics
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