Redox-manipulating nanocarriers for anticancer drug delivery: a systematic review
Tianjin University of Science and Technology · Tianjin University · +1 more institution
Abstract
Spatiotemporally controlled cargo release is a key advantage of nanocarriers in anti-tumor therapy. Various external or internal stimuli-responsive nanomedicines have been reported for their ability to increase drug levels at the diseased site and enhance therapeutic efficacy through a triggered release mechanism. Redox-manipulating nanocarriers, by exploiting the redox imbalances in tumor tissues, can achieve precise drug release, enhancing therapeutic efficacy while minimizing damage to healthy cells. As a typical redox-sensitive bond, the disulfide bond is considered a promising tool for designing tumor-specific, stimulus-responsive drug delivery systems (DDS). The intracellular redox imbalance caused by…
Citation impact
- FWCI
- 21.48
- Percentile
- 100%
- References
- 172
Authors
6- XMXuan MengCorresponding
Tianjin University of Science and Technology
- YSYongli Shen
Tianjin University of Science and Technology
- HZHuanyu Zhao
Tianjin University of Science and Technology
- XLXinlei Lu
Tianjin University of Science and Technology
- ZWZheng Wang
Tianjin University, Collaborative Innovation Center of Chemical Science and Engineering Tianjin
Topics & keywords
- Nanocarriers
- Chemistry
- Anticancer drug
- Pharmacology
- Drug delivery
- Nanotechnology
- Drug
- Medicine
- Good health and well-being