articleNucleic Acids ResearchOct 10, 2024GOLD OA

Comparative Toxicogenomics Database’s 20th anniversary: update 2025

APAllan Peter DavisTCThomas C. WiegersDSDaniela SciakyFBFern BarkalowMSMelissa Strong

North Carolina State University

PubMed
Indexed incrossrefdoajpubmed

Abstract

For 20 years, the Comparative Toxicogenomics Database (CTD; https://ctdbase.org) has provided high-quality, literature-based curated content describing how environmental chemicals affect human health. Today, CTD includes over 94 million toxicogenomic connections relating chemicals, genes/proteins, phenotypes, anatomical terms, diseases, comparative species, pathways and exposures. In this 20th year anniversary update, we reflect on CTD's remarkable growth and provide an overview of the increased data content and new features, including enhancements to the curation workflow (e.g. new exposure curation tool and expanded use of natural language processing), added functionality (e.g. improvements to CTD Tetramers…

Citation impact

181
total citations
FWCI
38.20
Percentile
100%
References
29
Citations per year

Authors

10

Topics & keywords

Topics
Keywords
  • Toxicogenomics
  • Data curation
  • Workflow
  • Biology
  • Database
  • Human health
  • Data science
  • Computational biology
UN Sustainable Development Goals
  • Industry, innovation and infrastructure
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