articleThe Lancet Infectious DiseasesOct 15, 2024HYBRID OA

Re-emergence of Oropouche virus between 2023 and 2024 in Brazil: an observational epidemiological study

Universidade Estadual de Campinas (UNICAMP) · University of Kentucky · +6 more institutions

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Abstract

Background

Oropouche virus is an arthropod-borne virus that has caused outbreaks of Oropouche fever in central and South America since the 1950s. This study investigates virological factors contributing to the re-emergence of Oropouche fever in Brazil between 2023 and 2024.

Methods

) to assess the susceptibility of the novel isolate and BeAn19991 isolate to antibody neutralisation, both in serum samples from people previously infected with Oropouche virus and in blood collected from mice that were inoculated with either of the strains.

Findings

titre of 640 [IQR 320-640] for BeAn19991 vs

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Funding