reviewMicrobial PathogenesisOct 30, 2024HYBRID OA

Phage therapy: A targeted approach to overcoming antibiotic resistance

University of East London · University of Arizona · +4 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

The rise of antibiotic-resistant bacterial infections has become a significant global health threat, necessitating the need for alternative therapeutic strategies. The use of bacteriophages—viruses that particularly infect and lyse bacteria—in phage therapy has resurfaced as a potentially effective substitute for conventional antibiotics. This narrative review aims to explore the mechanisms, applications, challenges, and prospects of phage therapy in combating antibiotic-resistant infections. A thorough analysis of the literature was carried out by exploring online databases, such as Google Scholar, PubMed, Scopus, and Web of Science. The search focused on peer-reviewed articles, clinical trials, and…

Citation impact

108
total citations
FWCI
46.36
Percentile
100%
References
149
Citations per year

Authors

7

Topics & keywords

Keywords
  • Phage therapy
  • Antibiotic resistance
  • Antibiotics
  • Antibiotic therapy
  • Microbiology
  • Medicine
  • Resistance (ecology)
  • Intensive care medicine
UN Sustainable Development Goals
  • Zero hunger
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