reviewEnvironmental Science & TechnologyOct 30, 2024HYBRID OA

The Global Threat from the Irreversible Accumulation of Trifluoroacetic Acid (TFA)

Norwegian Geotechnical Institute · Norwegian University of Science and Technology · +3 more institutions

PubMed
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Abstract

Trifluoroacetic acid (TFA) is a persistent and mobile substance that has been increasing in concentration within diverse environmental media, including rain, soils, human serum, plants, plant-based foods, and drinking water. Currently, TFA concentrations are orders of magnitude higher than those of other per- and polyfluoroalkyl substances (PFAS). This accumulation is due to many PFAS having TFA as a transformation product, including several fluorinated gases (F-gases), pesticides, pharmaceuticals, and industrial chemicals, in addition to direct release of industrially produced TFA. Due to TFA's extreme persistence and ongoing emissions, concentrations are increasing irreversibly. What remains less clear are…

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