Optimizing scaffold pore size for tissue engineering: insights across various tissue types
Nazarbayev University · Al-Farabi Kazakh National University
Abstract
Microenvironment, directly influencing cellular interactions, migration, nutrient transfer, vascularization, and the formation of functional tissues. For optimal tissue formation, scaffold design must account for various parameters, including material composition, morphology, mechanical properties, and cellular compatibility. This review highlights the importance of interconnected porosity and pore size, emphasizing their impact on cellular behavior and tissue formation across several tissue engineering domains, such as skin, bone, cardiovascular, and lung tissues. Specific pore size ranges enhance scaffold functionality for different tissues: small pores (∼1-2 µm) aid epidermal cell attachment in skin…
Citation impact
- FWCI
- 50.60
- Percentile
- 100%
- References
- 130
Authors
6Topics & keywords
- Scaffold
- Tissue engineering
- Regeneration (biology)
- Porosity
- Materials science
- Bone tissue
- Biomedical engineering
- Chemistry