Avian influenza A (H5N1) virus in dairy cattle: origin, evolution, and cross-species transmission
Texas Biomedical Research Institute · Prevention Institute · +6 more institutions
Abstract
Since the emergence of highly pathogenic avian influenza virus (HPAIV) H5N1 of clade 2.3.4.4b as a novel reassortant virus from subtype H5N8, the virus has led to a massive number of outbreaks worldwide in wild and domestic birds. Compared to the parental HPAIV H5N8 clade 2.3.4.4b, the novel reassortant HPAIV H5N1 displayed an increased ability to escape species barriers and infect multiple mammalian species, including humans. The virus host range has been recently expanded to include ruminants, particularly dairy cattle in the United States, where cattle-to-cattle transmission was reported. As with the avian 2.3.4.4.b H5N1 viruses, the cattle-infecting virus was found to transmit from cattle to other contact…
Citation impact
- FWCI
- 44.89
- Percentile
- 100%
- References
- 74
Authors
7- AMAhmed MostafaCorresponding
Texas Biomedical Research Institute, Prevention Institute, National Influenza Center, National Research Centre
- MMMahmoud M. Naguib
Uppsala University, University of Liverpool
- ANAitor Nogales
Département Santé Animale
- RSRamya S. Barre
Texas Biomedical Research Institute, Prevention Institute
- JPJames P. Stewart
University of Liverpool
Topics & keywords
- Influenza A virus subtype H5N1
- Outbreak
- Biology
- Virology
- Virus
- Transmission (telecommunications)
- Influenza A virus
- Clade
- Good health and well-being