Tailored Metal–Organic Framework‐Based Nanozymes for Enhanced Enzyme‐Like Catalysis

Abstract The global crisis of bacterial infections is exacerbated by the escalating threat of microbial antibiotic resistance. Nanozymes promise to provide ingenious solutions. Here, we reported a homogeneous catalytic structure of Pt nanoclusters with finely tuned metal–organic framework (ZIF‐8) channel structures for the treatment of infected wounds. Catalytic site normalization showed that the active site of the Pt aggregates structure with fine‐tuned pore modifications structure had a catalytic capacity of 14.903×10 5 min −1 , which was 18.7 times higher than that of the Pt particles in monodisperse state in ZIF‐8 (0.793×10 5 min −1 ). In situ tests revealed that the change from homocleavage to…

• NN
  National Natural Science Foundation of China

  Award: 22274022 and 21874022