An update on adverse health effects from exposure to PM2.5

The impact of fine particulate matter (PM2.5) on public health has become a global concern due to the mortality and morbidity it entails. Pathophysiological and epidemiological studies have demonstrated an association between PM2.5 and respiratory diseases, cardiovascular diseases, and neurological disorders. The underlying mechanisms through which PM2.5 adversely affects human health include the induction of oxidative stress, cytokine release, deoxyribonucleic acid (DNA) damage, altered gene expression, immune toxicity, inflammatory responses, and apoptosis. These outcomes drive the initiation and progression of various diseases. Notably, exposure to PM2.5 containing chemical compounds may translocate and…

• RU
  Rajamangala University of Technology Lanna
• UO
  University of Phayao
• TS
  Thailand Science Research and Innovation