Cross-Electrophile Coupling: Principles, Methods, and Applications in Synthesis

)-C(sp) bond formation. Additional chapters include alkene difunctionalization, alkyne difunctionalization, and formation of carbon-heteroatom bonds. Each chapter is generally organized with an initial summary of mechanisms followed by detailed figures and notes on methodological developments and ending with application notes in synthesis. While XEC is becoming an increasingly utilized approach in synthesis, its early stage of development means that optimal catalysts, ligands, additives, and reductants are still in flux. This review has collected data on these and various other aspects of the reactions to capture the state of the field. Finally, the data collected on the papers in this review is offered as…

• UO
  University of Wisconsin-Madison
• NI
  National Institute of General Medical Sciences

  Awards: R01 GM097243, T32 GM152341, F32 GM146357
• DO
  Division of Graduate Education

  Award: DGE-2137424
• DO
  Division of Chemistry

  Award: CHE-2154698