articleHuman Reproduction OpenJan 1, 2024GOLD OA

Evidence-based guideline: premature ovarian insufficiency,

NPNick PanayRARichard A. AndersonABAmy BennieMIMarcelle I. CedarsMDMelanie Davies

Queen Charlotte's and Chelsea Hospital · Imperial College London · +19 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

STUDY QUESTION: How should premature/primary ovarian insufficiency (POI) be diagnosed and managed based on the best available evidence from published literature? SUMMARY ANSWER: The current guideline provides 145 recommendations on symptoms, diagnosis, causation, sequelae, and treatment of POI. WHAT IS KNOWN ALREADY: Premature ovarian insufficiency (POI) presents a significant challenge to women's health, with far-reaching implications, both physically and emotionally. The potential implications include adverse effects on quality of life; fertility; and bone, cardiovascular, and cognitive health. Although hormone therapy (HT) can mitigate some of these effects, many questions still remain regarding the optimal…

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109
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23

Topics & keywords

Topics
Keywords
  • Premature ovarian insufficiency
  • Guideline
  • Premature ovarian failure
  • Medicine
  • Internal medicine
  • Gynecology
  • Pathology
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