Hepatocellular carcinoma: updates on epidemiology, surveillance, diagnosis and treatment
University of Maryland, Baltimore · University of Maryland Medical Center Midtown Campus · +11 more institutions
Abstract
Hepatocellular carcinoma (HCC) is a major global burden, ranking as the third leading cause of cancer-related mortality. HCC due to chronic hepatitis B virus (HBV) or C virus (HCV) infection has decreased due to universal vaccination for HBV and effective antiviral therapy for both HBV and HCV, but HCC related to metabolic dysfunction-associated steatotic liver disease and alcohol-associated liver disease is increasing. Biannual liver ultrasonography and serum α-fetoprotein are the primary surveillance tools for early HCC detection among high-risk patients (e.g., cirrhosis, chronic HBV). Alternative surveillance tools such as blood-based biomarker panels and abbreviated magnetic resonance imaging (MRI) are…
Citation impact
- FWCI
- 59.23
- Percentile
- 100%
- References
- 223
Authors
8- SYSoo Young HwangCorresponding
University of Maryland, Baltimore, University of Maryland Medical Center Midtown Campus
- PDPojsakorn Danpanichkul
Texas Tech University, Texas Tech University Health Sciences Center
- VGVatche G. Agopian
- NMNeil Mehta
University of California, San Francisco
- NDNeehar D. Parikh
University of Michigan
Topics & keywords
- Hepatocellular carcinoma
- Epidemiology
- Medicine
- Surveillance, Epidemiology, and End Results
- Oncology
- Internal medicine
- Environmental health
- Cancer registry
- Good health and well-being